Search for: [Abstract = "ncentrations were assessed in particular groups in the same manner as abovementioned. Additionally endoscopic biopsies of gastric mucosa of fundus, body and prepyloric region were performed in every patient. In patients suffering from gastric cancer biopsies of tumor were also performed. Biopsy specimens were examined to assess ghrelin and gastrin mRNA expression in gastric mucosa. The study showed significant influence of Hp infection on ghrelin and gastrin plasma concentrations. The highest ghrelin concentrations were found in patients from the group 2 – i.e. patients with prepyloric gastritis with Hp infection and concomitant duodenal ulcer \- 503 pg\/ml\; 95% CI\: 285,1 – 886,2. Ghrelin concentrations were found to be the lowest in the group 3 \- – 144 pg\/ml\; 95% CI\: 93 – 222. In the group 1 – patients with gastric cancer and concomitant Hp infection – ghrelin concentrations before the surgical operation amounted 203 pg\/ml\; 95% CI\: 161 – 257,4, while in the group 4 \(control group\) \- 255 pg\/ml\; 95% CI\: 160,5 – 406,3. In patients from the group 1 after total gastrectomy ghrelin concentrations proved to significantly decrease to the level of 135 pg\/ml\; 95% CI\: 83 – 220, that was not found in patients after distal stomach resection – 220 pg\/ml\; 95% CI\: 103\-473,2. Higher ghrelin plasma concentrations were also found in patients with gastric cancer localized not in the fundus as co"]

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